Interventions to Improve Antiretroviral Therapy Adherence Among Adolescents in Low-and Middle-Income Countries: A Systematic Review of the Literature

This article is a systematic review of the peer-reviewed and grey literature published between 2010 and 2015 to identify interventions designed to improve antiretroviral adherence among adults and adolescents in low- and middle-income countries. The authors conducted searches on PubMed, Web of Science, Popline, the AIDSFree Resource Library, and the USAID Development Experience Clearinghouse to identify relevant publications and used the NIH NHLBI Quality Assessment Tools to assess the quality and risk of bias of each study.  Notably, the authors found that there was little evidence on how to improve adherence with adolescents and recommended that there is a need to develop and test strategies and interventions for this priority population.