PREVIEW

Evidence-based practices for retention in care of mother-infant pairs in the context of eliminating mother-to-child transmission of HIV in Eastern and Southern Africa: A summary with guidance for scale up

July 24, 2019

For countries to achieve the elimination of mother-to-child transmission of HIV (EMTCT), mothers and their infants must remain in care through the cessation of breastfeeding and beyond. While many countries in Eastern and Southern Africa have made significant strides in reducing mother-to-child transmission (MTCT) rates at six weeks, the final MTCT rates at the end… View Article

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PREVIEW

Start Free Stay Free AIDS Free 2019 Report

July 22, 2019

This progress report reviews recent gains, new developments and remaining challenges as countries approach the 2020 targets of the Start Free Stay Free AIDS Free framework. It summarizes country progress at the end of 2018, and the results are mixed. The global targets set for 2018 have been missed by a wide margin in some… View Article

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PREVIEW

Neurodevelopmental effects of ante-partum and post-partum antiretroviral exposure in HIV-exposed and uninfected children versus HIV-unexposed and uninfected children in Uganda and Malawi: a prospective cohort study

July 15, 2019

The effect of prolonged antiretroviral therapy (ART) exposure on newborn neurological development is a major concern for parents and healthcare workers. Findings, from a prospective cohort study in Uganda and Malawi show that in the first five years of life the neurological development of HIV-exposed but uninfected infants, exposed to maternal antiretrovirals before and after… View Article

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PREVIEW

Viral suppression among children and their caregivers living with HIV in western Kenya

July 15, 2019

Despite the central role of caregivers in managing HIV treatment for children living with HIV, viral suppression within caregiver–child dyads in which both members are living with HIV is not well described. The objective of this study was to describe the association between child and caregiver viral suppression and the factors that influence viral non-suppression… View Article

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PREVIEW

Cell Phone Counseling Improves Retention of Mothers With HIV Infection in Care and Infant HIV Testing in Kisumu, Kenya: A Randomized Controlled Study

June 27, 2019

While studies have looked at the effectiveness of cell phones in delivering short reminders and messages to improve health care, this study evaluated the effectiveness of a structured cell phone counseling intervention, informed by behavioral theory and delivered by trained counselors. The counseling was designed to improve maternal retention in care until 14 weeks after… View Article

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PREVIEW

Financial education for HIV-vulnerable youth, orphans and vulnerable children: a systematic review of outcome evidence

June 18, 2019

This study was designed to fill in some of the gaps in knowledge pertaining to financial education for OVC and improvements in health and HIV prevention. This review supports emerging evidence that plural interventions, combining sexual and reproductive health with financial education, are associated with positive health and economic outcomes for vulnerable youth and children… View Article

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PREVIEW

Communicating with children about life-threatening conditions

June 18, 2019

This two-paper Series summarizes the available evidence on communication with children about their own life-threatening disease and about a life-threatening disease in a parent. The effects on emotional, behavioral, and social outcomes, illness-related factors, and barriers and challenges to communication are summarized. Children’s developmental stages of understanding illness and death are highlighted as important background… View Article

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PREVIEW

Validation of a New Three-Item Self-Report Measure for Medication Adherence

June 18, 2019

Using electronic drug monitoring (EDM) as a gold standard, this study validated testing of a rigorously developed three-item medication adherence self-report scale, using both HIV antiretroviral medications and other medications. The results support the validity of the self-report scale, and suggest that it can be used for all classes of medications. In clinical care the… View Article

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PREVIEW

Understanding the Relationships Between HIV and Child Marriage: Conclusions From an Expert Consultation

June 5, 2019

Girls Not Brides and UNICEF convened an expert consultation to examine the evidence pertaining to the relationship between HIV and early marriage. Understanding about that relationship has changed in the past two decades and experts are now considering a more nuanced understanding of how early marriage relates to HIV. This article provides four recommendations and… View Article

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PREVIEW

Task-shifted interventions for depression delivered by lay primary health-care workers in low-income and middle-income countries

May 17, 2019

As we think more and more about how to integrate mental health support in OVC programs, the results of a cluster-randomised trial in Nigeria showed that task-shifted interventions delivered by lay health workers were associated with remission in more than three-quarters of patients with moderate to severe depression. The two interventions they tried were: Fully… View Article

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